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Neil Chi Lab

About the Neil Chi Lab

We're gaining insights into the molecular mechanisms of cardiovascular diseases and the developmental pathways that help create the cardiovascular system. We hope to translate our findings into new methods of detecting and treating cardiovascular diseases, the leading causes of morbidity and mortality in children and adults around the world.

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Support Our Work

Your gifts help us bridge the gap between discovery and patient care. Contact Malcolm Aste, 858-657-5327, to partner with us.


Dr. Neil Chi


Neil C. Chi, MD, PhD, is director of the UCSD Cardiac Tissue Harvest and Biorepository Core and UCSD MD-PhD Medical Scientist Training Program (MSTP). He focuses on cardiac development and regeneration; novel disease gene targets and treatment; and gene and stem cell based therapies.


  • Congratulations to Dekker Deacon on his Nature Biomedical Engineering paper and cover that explores the genetic complexity of human dilated cardiomyopathy using mouse and human pluripotent stem cell models.
  • Congratulations to Manuel Galvez-Santisteban and Danni Chen on their eLife paper that investigates the impact of hemodynamics on cardiac regeneration in zebrafish.
  • Congratulations to Ting Li on his co-first author Nature Genetics paper with Yanxiao Zhang, which uncovers a novel role for retrotransposons in creating topologically associating domains in human pluripotent stem cells.
  • Congratulations to Jie Ren on her Developmental Cell paper and cover that reveals a role for Wnt5 in specifying Nkx2.5+ cardiac progenitors to pacemaker cardiomyocytes using zebrafish and human pluripotent stem cell models.
  • Congratulations to Qingquan Zhang and Dan Carlin on their Circulation Research paper that identifies and characterizes a new field of cardiac progenitors that contribute to creating the mammalian heart
journal covers

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