Skip to main content

The Seaweed Canyon Cardiovascular Physiology Laboratory

Seaweed Cardiovascular Physiology Core Services

(Not limited to the following)

  1. Invasive left heart and right heart functions and pathological cardiac models studies:
    • Hemodynamics with or without pressure volume loops studies with various agents' injections. 
    • Blood pressure measurement in conscience mice with telemetry, in anesthetized mice with catheters.
    • Electrocardiogram (ECG) in conscience mice using telemetry, or under anesthetized with isoflurane
    • Intra-cardiac pacing with electric programming stimulation
    • Transverse aortic constriction (TAC) and post TAC pressure gradient measurements
    • Myocardial infarction
    • Ischemia reperfusion
    • Mini pump implantation
    • Neonatal mice apex resection
    • Aortic stenosis wire injury
    • Intra- cardiac, ventricles and venous injections of virus, cells or experiment agents.
    • Blood and tissue collections

       2.     Non-invasive cardiac function studies:

    •  Echocardiography: 
      • Pulsed-Wave Doppler (aortic flow and pulmonary flow)
      • 2D (chamber size and function, aortic arch size)
      • 4 Chamber view with Pulsed-Wave Doppler and Tissue Doppler
      • Strain Analysis
    • Other measurements
      • Tail cuff
      • Treadmill



Dr. Eric D. Adler and Dr. Ju Chen, Co-Directors, 2020-present

Dr. Kirk L. Peterson, Associate Director, 1988 – 2005, and Director, 2005-2020

Dr. John Ross, Jr., Director, 1972 - 2005

Dr. Eugene Braunwald, Director, 1968 - 1972

Dr. Dean Franklin, Founding Director, 1965-1970