Adult Congenital Heart Disease Research

Language Barriers in Patients With Cardiovascular Disease: A Mixed Methods Study.

Edward Wang, Tala Al-Rousan, Wali Mansour, Diego Oliva, Nicole Herrick, Birju Desai, Laith Alshawabkeh JACC: Advances, Volume 1, Issue 4, 2022, 100077, ISSN 2772-963X. doi: 10.1016/j.jacadv.2022.100077.

Metabolomic Profiles Differentiate Scleroderma-PAH From Idiopathic PAH and Correspond With Worsened Functional Capacity.

Alotaibi M, Shao J, Pauciulo MW, Nichols WC, Hemnes AR, Malhotra A, Kim NH, Yuan JX, Fernandes T, Kerr KM, Alshawabkeh L, Desai AA, Bujor AM, Lafyatis R, Watrous JD, Long T, Cheng S, Chan SY, Jain M.Chest. 2023 Jan;163(1):204-215. doi: 10.1016/j.chest.2022.08.2230. Epub 2022 Sep 7.PMID: 36087794

A case of double-chambered left ventricle presenting with heart failure symptoms.

Ahmad A, Carazo M.Cardiol Young. 2022 Nov 17:1-3. doi: 10.1017/S1047951122003614. Online ahead of print.PMID: 36384977

The role of sensitization in post-transplant outcomes in adults with congenital heart disease sensitization in adults with congenital heart disease.

Laith Alshawabkeh, Nicole L. Herrick, Alexander R. Opotowsky, Tajinder P. Singh, Michael Landzberg, Marcus A. Urey, Wida Cherikh, Joseph W. Rossano, Michael M. Givertz International Journal of Cardiology Congenital Heart Disease, Volume 8, 2022, 100384, ISSN 2666-6685 doi: 10.1016/j.ijcchd.2022.100384.

Transvenous laser lead extraction in patients with congenital complete heart block.

Darden D, Boateng BA, Tseng AS, Alshawabkeh L, Pollema T, Cha YM, Birgersdotter-Green U.Heart Rhythm. 2022 Jul;19(7):1158-1164. doi: 10.1016/j.hrthm.2022.02.031. Epub 2022 Mar 4.PMID: 35257976

Selective Valve Removal for Melody Valve Endocarditis: Practice Variations in a Multicenter Experience.

Davtyan A, Guyon PW, El-Sabrout HR, Ponder R, Ramchandar N, Weber R, Zayed W, Ratnayaka K, Nigro JJ, Moore JW, Bauser-Heaton H, Alshawabkeh L, Reeves RR, Levi D, Aboulhosn J, Justino H, Bradley J, El-Said HG.Pediatr Cardiol. 2022 Apr;43(4):894-902. doi: 10.1007/s00246-021-02801-z. Epub 2021 Dec 11.PMID: 34894280

Epidemiology of cardiovascular disease and its risk factors among refugees and asylum seekers: Systematic review and meta-analysis.

Al-Rousan T, AlHeresh R, Saadi A, El-Sabrout H, Young M, Benmarhnia T, Han BH, Alshawabkeh L.Int J Cardiol Cardiovasc Risk Prev. 2022 Feb 10;12:200126. doi: 10.1016/j.ijcrp.2022.200126. eCollection 2022 Mar.PMID: 35199106

Laparoscopic Surgery Requiring Abdominal Insufflation in Patients With Congenital Heart Disease.

Herrick NL, Bickler S, Maus T, Kim YY, Aboulhosn JA, Nigro J, El-Said H, Bhatt AB, Alshawabkeh L.J Cardiothorac Vasc Anesth. 2022 Mar;36(3):707-712. doi: 10.1053/j.jvca.2021.05.005. Epub 2021 May 12.PMID: 34175203

Alcohol use is prevalent among adults with the fontan circulation but does not correlate with liver disease

Shravani Chintakindi, Bendelyn Asante Boateng, Irine Vodkin, Nicole Herrick, Maria Moceri, Deborah Raleigh, Edward Wang, Howaida El-Said, Ryan Reeves, Jose Silva Sepulveda, Laith Alshawabkeh. Atherosclerosis. 2022 Aug;354:15-22. doi: 10.1016/j.ijcchd.2022.100339. International Journal of Cardiology Congenital Heart Disease, Volume 7, 2022, 100339, ISSN 2666-6685

Priorities and Understanding of Pregnancy Among Women With Congenital Heart Disease: A Mixed-Methods Study.

Nicole Herrick, Tala Al-Rousan, Carla Rodriguez, Ji Hae Lee, Anne Marie Valente, Jordan Stone, Gladys Ramos, Bendelyn Asante-Boateng, Howaida El-Said, Maria Moceri-Casas, and Laith Alshawabkeh. JACC Adv. 2022 Oct, 1 (4) 100112. doi: 10.1016/j.jacadv.2022.100112.

Evidence of maternal vascular malperfusion in placentas of women with congenital heart disease.

Rodríguez-Soto AE, Pham D, Tran T, Meads M, Stanley V, Melber D, Lamale-Smith L, Zhang-Rutledge K, Rakow-Penner R, Alshawabkeh L, Parast MM, Contijoch F.Placenta. 2022 Jan;117:209-212. doi: 10.1016/j.placenta.2021.12.016. Epub 2021 Dec 18.PMID: 34953287

Prevalence of Venovenous Shunting and High-Output State Quantified with 4D Flow MRI in Patients with Fontan Circulation.

Raimondi F, Martins D, Coenen R, Panaioli E, Khraiche D, Boddaert N, Bonnet D, Atkins M, El-Said H, Alshawabkeh L, Hsiao A.Radiol Cardiothorac Imaging. 2021 Dec 16;3(6):e210161. doi: 10.1148/ryct.210161. eCollection 2021 Dec.PMID: 34934948

Methamphetamine-Associated Heart Failure Hospitalizations Across the United States: Geographic and Social Disparities.

Dickson SD, Thomas IC, Bhatia HS, Nishimura M, Mahmud E, Tu XM, Lin T, Adler E, Greenberg B, Alshawabkeh L.J Am Heart Assoc. 2021 Aug 17;10(16):e018370. doi: 10.1161/JAHA.120.018370. Epub 2021 Aug 7.PMID: 34365802

COVID-19 in Adults With Congenital Heart Disease.

Broberg CS, Kovacs AH, Sadeghi S, Rosenbaum MS, Lewis MJ, Carazo MR, Rodriguez FH 3rd, Halpern DG, Feinberg J, Galilea FA, Baraona F, Cedars AM, Ko JM, Porayette P, Maldonado J, Sarubbi B, Fusco F, Frogoudaki AA, Nir A, Chaudhry A, John AS, Karbassi A, Hoskoppal AK, Frischhertz BP, Hendrickson B, Bouma BJ, Rodriguez-Monserrate CP, Broda CR, Tobler D, Gregg D, Martinez-Quintana E, Yeung E, Krieger EV, Ruperti-Repilado FJ, Giannakoulas G, Lui GK, Ephrem G, Singh HS, Almeneisi HM, Bartlett HL, Lindsay I, Grewal J, Nicolarsen J, Araujo JJ, Cramer JW, Bouchardy J, Al Najashi K, Ryan K, Alshawabkeh L, Andrade L, Ladouceur M, Schwerzmann M, Greutmann M, Meras P, Ferrero P, Dehghani P, Tung PP, Garcia-Orta R, Tompkins RO, Gendi SM, Cohen S, Klewer S, Hascoet S, Mohammadzadeh S, Upadhyay S, Fisher SD, Cook S, Cotts TB, Aboulhosn JA.J Am Coll Cardiol. 2021 Apr 6;77(13):1644-1655. doi: 10.1016/j.jacc.2021.02.023.PMID: 33795039

4D Flow MRI Quantification of Congenital Shunts: Comparison to Invasive Catheterization.

Horowitz MJ, Kupsky DF, El-Said HG, Alshawabkeh L, Kligerman SJ, Hsiao A.Radiol Cardiothorac Imaging. 2021 Apr 1;3(2):e200446. doi: 10.1148/ryct.2021200446. eCollection 2021 Apr.PMID: 33969306

Percutaneous mitral valve repair in adults with congenital heart disease: Report of the first case-series.

Alshawabkeh L, Mahmud E, Reeves R.Catheter Cardiovasc Interv. 2021 Feb 15;97(3):542-548. doi: 10.1002/ccd.29238. Epub 2020 Sep 8.PMID: 32898313

Single-Barrel, Double-Barrel, and Fenestrated Endografts to Facilitate Transcatheter Pulmonary Valve Replacement in Large RVOT.

Kamioka N, Babaliaros VC, Lisko JC, Sahu A, Shashidharan S, Carazo MR, Jokhadar M, Rodriguez FH 3rd, Book WM, Gleason PT, Keeling WB, Jaber W, Block PC, Lederman RJ, Greenbaum AB, Kim DW.JACC Cardiovasc Interv. 2020 Dec 14;13(23):2755-2765. doi: 10.1016/j.jcin.2020.08.024.PMID: 33303113

Impact of Pregnancy on Ventricular Strain in Women with Repaired Tetralogy of Fallot.

Duarte VE, Graf JA, Gauvreau K, Easter SR, Drakeley SC, Carazo MR, Economy KE, Valente AM, Harrild DM.Pediatr Cardiol. 2020 Dec;41(8):1795-1799. doi: 10.1007/s00246-020-02447-3. Epub 2020 Sep 11.PMID: 32915291

Assessment and management of heart failure in the systemic right ventricle.

Carazo M, Andrade L, Kim Y, Wilson W, Wu FM.Heart Fail Rev. 2020 Jul;25(4):609-621. doi: 10.1007/s10741-020-09914-2.PMID: 31970551

Mechanisms for heart failure in systemic right ventricle.

Andrade L, Carazo M, Wu F, Kim Y, Wilson W.Heart Fail Rev. 2020 Jul;25(4):599-607. doi: 10.1007/s10741-019-09902-1.PMID: 31853794

Prevalence and Prognostic Association of a Clinical Diagnosis of Depression in Adult Congenital Heart Disease: Results of the Boston Adult Congenital Heart Disease Biobank.

Carazo MR, Kolodziej MS, DeWitt ES, Kasparian NA, Newburger JW, Duarte VE, Singh MN, Opotowsky AR.J Am Heart Assoc. 2020 May 5;9(9):e014820. doi: 10.1161/JAHA.119.014820. Epub 2020 Apr 28.PMID: 32342722

Significance of Aortopulmonary Collaterals in a Single-Ventricle Patient Supported With a HeartMate 3.

Smith M, El-Said H, Pretorius V, Mendenhall M, Thomas T, Reeves RR, Silva Enciso J, Alshawabkeh L, Nigro J, Adler ED, Urey MA.Circ Heart Fail. 2020 Apr;13(4):e006473. doi: 10.1161/CIRCHEARTFAILURE.119.006473. Epub 2020 Apr 6.PMID: 32248696

Clinical Characteristics and Outcomes of Patients With Heart Failure and Methamphetamine Abuse.

Thomas IC, Nishimura M, Ma J, Dickson SD, Alshawabkeh L, Adler E, Maisel A, Criqui MH, Greenberg B.J Card Fail. 2020 Mar;26(3):202-209. doi: 10.1016/j.cardfail.2019.10.002. Epub 2019 Oct 13.PMID: 31618697

The Impact of Substance Abuse on Heart Failure Hospitalizations.

Nishimura M, Bhatia H, Ma J, Dickson SD, Alshawabkeh L, Adler E, Maisel A, Criqui MH, Greenberg B, Thomas IC.Am J Med. 2020 Feb;133(2):207-213.e1. doi: 10.1016/j.amjmed.2019.07.017. Epub 2019 Jul 29.PMID: 31369724

Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank.

Opotowsky AR, Carazo M, Singh MN, Dimopoulos K, Cardona-Estrada DA, Elantably A, Waikar SS, Mc Causland FR, Veldtman G, Grewal J, Gray C, Loukas BN, Rajpal S.Am Heart J. 2019 Aug;214:142-155. doi: 10.1016/j.ahj.2019.04.018. Epub 2019 May 22.PMID: 31203159

Evaluation of Fontan liver disease: Correlation of transjugular liver biopsy with magnetic resonance and hemodynamics.

Silva-Sepulveda JA, Fonseca Y, Vodkin I, Vaughn G, Newbury R, Vavinskaya V, Dwek J, Perry JC, Reshamwala P, Baehling C, Lyon J, Davis C, Lee JW, El-Sabrout H, Shahbah D, Alshawabkeh L, Moore JW, El-Said H.Congenit Heart Dis. 2019 Jul;14(4):600-608. doi: 10.1111/chd.12770. Epub 2019 Apr 30.PMID: 31038848

Contemporary ACHD training and the reality of the field in the United States.

Ephrem G, Alshawabkeh L.Int J Cardiol. 2019 Feb 15;277:85-89. doi: 10.1016/j.ijcard.2018.08.086. Epub 2018 Sep 1.PMID: 30195839

Disparities in Wait-List Outcomes for Adults With Congenital Heart Disease Listed for Heart Transplantation Before and Since Revision of Status I Listing.

Alshawabkeh L, Opotowsky AR, Carter KD, Givertz MM, Landzberg MJ, Urey MA, Bartlett H.Am J Cardiol. 2018 Nov 15;122(10):1761-1764. doi: 10.1016/j.amjcard.2018.08.013. Epub 2018 Aug 21.PMID: 30236623

Relationship of Red Cell Distribution Width to Adverse Outcomes in Adults With Congenital Heart Disease (from the Boston Adult Congenital Heart Biobank).

Alshawabkeh L, Rajpal S, Landzberg MJ, Emani S, Ephrem G, Gray C, Singh MN, Wu F, Opotowsky AR.Am J Cardiol. 2018 Nov 1;122(9):1557-1564. doi: 10.1016/j.amjcard.2018.07.019. Epub 2018 Aug 3.PMID: 30217370

Prospective cohort study of C-reactive protein as a predictor of clinical events in adults with congenital heart disease: results of the Boston adult congenital heart disease biobank.

Opotowsky AR, Valente AM, Alshawabkeh L, Cheng S, Bradley A, Rimm EB, Landzberg MJ.Eur Heart J. 2018 Sep 7;39(34):3253-3261. doi: 10.1093/eurheartj/ehy362.PMID: 30010900

Association of Albuminuria With Major Adverse Outcomes in Adults With Congenital Heart Disease: Results From the Boston Adult Congenital Heart Biobank.

Rajpal S, Alshawabkeh L, Almaddah N, Joyce CM, Shafer K, Gurvitz M, Waikar SS, Mc Causland FR, Landzberg MJ, Opotowsky AR.JAMA Cardiol. 2018 Apr 1;3(4):308-316. doi: 10.1001/jamacardio.2018.0125.PMID: 29541749

Thermodilution vs Estimated Fick Cardiac Output Measurement in Clinical Practice: An Analysis of Mortality From the Veterans Affairs Clinical Assessment, Reporting, and Tracking (VA CART) Program and Vanderbilt University.

Opotowsky AR, Hess E, Maron BA, Brittain EL, Barón AE, Maddox TM, Alshawabkeh LI, Wertheim BM, Xu M, Assad TR, Rich JD, Choudhary G, Tedford RJ.JAMA Cardiol. 2017 Oct 1;2(10):1090-1099. doi: 10.1001/jamacardio.2017.2945.PMID: 28877293

Current Role of Blood and Urine Biomarkers in the Clinical Care of Adults with Congenital Heart Disease.

Rajpal S, Alshawabkeh L, Opotowsky AR.Curr Cardiol Rep. 2017 Jun;19(6):50. doi: 10.1007/s11886-017-0860-z.PMID: 28432659

Prognostic Utility of the Braden Scale and the Morse Fall Scale in Hospitalized Patients With Heart Failure.

Carazo M, Sadarangani T, Natarajan S, Katz SD, Blaum C, Dickson VV.West J Nurs Res. 2017 Apr;39(4):507-523. doi: 10.1177/0193945916664077. Epub 2016 Aug 20.PMID: 27531001

Anticoagulation During Pregnancy: Evolving Strategies With a Focus on Mechanical Valves.

Alshawabkeh L, Economy KE, Valente AM.J Am Coll Cardiol. 2016 Oct 18;68(16):1804-1813. doi: 10.1016/j.jacc.2016.06.076.PMID: 27737747

Burden of Heart Failure in Adults with Congenital Heart Disease.

Alshawabkeh LI, Opotowsky AR.Curr Heart Fail Rep. 2016 Oct;13(5):247-254. doi: 10.1007/s11897-016-0301-0.PMID: 27485737

Wait-List Outcomes for Adults With Congenital Heart Disease Listed for Heart Transplantation in the U.S.

Alshawabkeh LI, Hu N, Carter KD, Opotowsky AR, Light-McGroary K, Cavanaugh JE, Bartlett HL.J Am Coll Cardiol. 2016 Aug 30;68(9):908-17. doi: 10.1016/j.jacc.2016.05.082.PMID: 27561764

Clinical pharmacology relevant to older adults with cardiovascular disease.

Brenes-Salazar JA, Alshawabkeh L, Schmader KE, Hanlon JT, Forman DE.J Geriatr Cardiol. 2015 May;12(3):192-5. doi: 10.11909/j.issn.1671-5411.2015.03.018.PMID: 26089839

Expanding pseudoaneurysm compressing the coronary arteries and causing cardiogenic shock.

Maliske SM, Alshawabkeh L, Schouweiler K, Sigurdsson G.J Cardiovasc Comput Tomogr. 2015 May-Jun;9(3):230-1. doi: 10.1016/j.jcct.2014.12.003. Epub 2014 Dec 26.PMID: 25708010

Years of able life in older persons--the role of cardiovascular imaging and biomarkers: the Cardiovascular Health Study.

Alshawabkeh LI, Yee LM, Gardin JM, Gottdiener JS, Odden MC, Bartz TM, Arnold AM, Mukamal KJ, Wallace RB.J Am Heart Assoc. 2015 Apr 23;4(4):e001745. doi: 10.1161/JAHA.114.001745.PMID: 25907126

Outcomes of a preoperative "bridging" strategy with glycoprotein IIb/IIIa inhibitors to prevent perioperative stent thrombosis in patients with drug-eluting stents who undergo surgery necessitating interruption of thienopyridine administration.

Alshawabkeh LI, Prasad A, Lenkovsky F, Makary LF, Kandil ES, Weideman RA, Kelly KC, Rangan BV, Banerjee S, Brilakis ES.EuroIntervention. 2013 Jun 22;9(2):204-11. doi: 10.4244/EIJV9I2A35.PMID: 23454910

Systematic review of the frequency and outcomes of non-cardiac surgery after drug-eluting stent implantation.

Alshawabkeh LI, Banerjee S, Brilakis ES.Hellenic J Cardiol. 2011 Mar-Apr;52(2):141-8.PMID: 21478124